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Health problems that research has shown to be associated with the MTHFR genetic mutation include: ADHD Autism Anxiety Migraines Depression Colon Cancer Blood clots Thyroid issues Chronic fatigue Hormonal issues Digestive disorders Autoimmune diseases Cardiovascular disease Neural tube defects in pregnancy If you have one or more of the issues listed above, you should consider working with a functional medicine provider who can help you peel back the layers of your health to identify the root cause

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It is particularly beneficial for individuals with autoimmune conditions, as it helps to balance the immune system and enhance T-cell function

SAM is converted to homocysteine after its methyl group is donated in a variety of metabolic pathways, including the synthesis of carnitine from lysine

In adults, these defects are usually characterized by the accumulation of medium-chain and long-chain (3-hydroxy) carnitine derivatives, and they are associated with lipotoxicity in several organs that can lead to life-threatening complications and comorbidities